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Tbio
EMP1
Epithelial membrane protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000256951
  • ENSP00000256951
  • ENSG00000134531
  • ENST00000396301
  • ENSP00000379595

Symbol
  • B4B
  • TMP
  • TMP
  • CL-20
  • EMP-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
1
transcription factor perturbation
1
PubMedID
0.98
kinase perturbation
0.97
small molecule perturbation
0.89


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 554.23   (req: < 5)
Gene RIFs: 21   (req: <= 3)
Antibodies: 107   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 554.23   (req: >= 5)
Gene RIFs: 21   (req: > 3)
Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (25)
PTH
Tbio
Novelty:  0.00003263
Score:  0.67
Data Source:  STRINGDB
EPOR
Tclin
Novelty:  0.00134388
Score:  0.67
Data Source:  STRINGDB
FGF23
Tclin
Novelty:  0.00047318
Score:  0.67
Data Source:  STRINGDB
SLC34A3
Tbio
Family:  Transporter
Novelty:  0.01738977
Score:  0.63
Data Source:  STRINGDB
MYO1A
Tbio
Novelty:  0.00942771
Score:  0.622
Data Source:  STRINGDB
MAEA
Tbio
Novelty:  0.00833813
Score:  0.576
Data Source:  STRINGDB
CYREN
Tbio
Novelty:  0.00278834
Score:  0.553
Data Source:  STRINGDB
CYP27B1
Tchem
Family:  Enzyme
Novelty:  0.00147574
Score:  0.54
Data Source:  STRINGDB
DMP1
Tbio
Novelty:  0.03114505
Score:  0.519
Data Source:  STRINGDB
CGN
Tbio
Novelty:  0.01097394
Score:  0.517
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
3
4
9
96.5
serum alanine aminotransferase measurement
1
1
1
75.9
serum albumin measurement
3
3
3
63.1
educational attainment
1
2
2
57.3
gut microbiome measurement
1
1
1
34.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
9
96.5
serum alanine aminotransferase measurement
1
75.9
serum albumin measurement
3
63.1
educational attainment
2
57.3
gut microbiome measurement
1
34.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
epithelial membrane protein 1
VGNC:5363
741239
Macaque
epithelial membrane protein 1
698319
Mouse
MGI:107941
13730
Rat
RGD:2552
25314
Dog
epithelial membrane protein 1
VGNC:40352
486676
Species
Name
OMA
EggNOG
Inparanoid
Chimp
epithelial membrane protein 1
Macaque
epithelial membrane protein 1
Mouse
Rat
Dog
epithelial membrane protein 1
Publication Statistics
PubMed Score 554.23
PubMed score by year
PubTator Score 123.63
PubTator score by year
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Related Publications
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PMID
Year
Title