Tbio PNLIPRP1 Inactive pancreatic lipase-related protein 1

Protein Summary

Description

May function as inhibitor of dietary triglyceride digestion. Lacks detectable lipase activity towards triglycerides, diglycerides, phosphatidylcholine, galactolipids or cholesterol esters (in vitro) (By similarity).

Uniprot Accession IDs

• P54315
• Q68D83
• Q68DR6
• Q8TAU2
• Q9BS82
• PL-RP1

Gene Name

• PNLIPRP1

Ensembl ID

• ENST00000358834
• ENSP00000351695
• ENSG00000187021
• ENST00000528052
• ENSP00000433933

Symbol

• PLRP1
• PLRP1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
metabolite	1
protein domain	0.92
gene perturbation	0.84
disease perturbation	0.49
kinase perturbation	0.48

Protein Classes

PANTHER Classes

Protein / Storage Protein / Inactive Pancreatic Lipase-related Protein 1

Protein / Hydrolase / Lipase / Inactive Pancreatic Lipase-related Protein 1

Protein / Hydrolase / Esterase / Inactive Pancreatic Lipase-related Protein 1

DTO Classes

Protein / Enzyme / Hydrolase / Lipase / Inactive Pancreatic Lipase-related Protein 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.12   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 68   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 30.12   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 68   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0