SLC16A1
Monocarboxylate transporter 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
drug perturbation | 1 | ||
transcription factor binding site profile | 0.92 | ||
kinase perturbation | 0.91 | ||
drug | 0.89 | ||
histone modification site profile | 0.86 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Basigin interactions | ||||
Reactome | Cell surface interactions at the vascular wall | ||||
Reactome | Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) | ||||
Reactome | Disease | ||||
Reactome | Disorders of transmembrane transporters | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Basigin interactions | ||||
Cell surface interactions at the vascular wall | ||||
Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) | ||||
Disease | ||||
Disorders of transmembrane transporters | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
refractive error measurement | 2 | 2 | 1 | 5.8 | 64.2 | |||||
refractive error measurement | 2 | 2 | 1 | 5.8 | 64.2 | |||||
age at onset | 1 | 1 | 0 | 5.8 | 28.1 | |||||
age at onset | 1 | 1 | 0 | 5.8 | 28.1 | |||||
Myopia | 1 | 1 | 0 | 5.8 | 28.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
refractive error measurement | 1 | 5.8 | 64.2 | ||||
refractive error measurement | 1 | 5.8 | 64.2 | ||||
age at onset | 0 | 5.8 | 28.1 | ||||
age at onset | 0 | 5.8 | 28.1 | ||||
Myopia | 0 | 5.8 | 28.1 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | solute carrier family 16 member 1 | 706593 | ||||||
Mouse | MGI:106013 | 20501 | ||||||
Rat | RGD:3690 | 25027 | ||||||
Dog | solute carrier family 16 member 1 | VGNC:46235 | 475856 | |||||
Horse | solute carrier family 16 member 1 | VGNC:50886 | 100009694 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | solute carrier family 16 member 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | solute carrier family 16 member 1 | |||||
Horse | solute carrier family 16 member 1 | |||||
PMID | Year | Title |
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