MAPK12
Mitogen-activated protein kinase 12
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.98 | ||
kinase perturbation | 0.88 | ||
protein domain | 0.85 | ||
biological process | 0.84 | ||
PubMedID | 0.76 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of PPARGC1A (PGC-1alpha) by phosphorylation | ||||
Reactome | Axon guidance | ||||
Reactome | DSCAM interactions | ||||
Reactome | Developmental Biology | ||||
Reactome | Immune System | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of PPARGC1A (PGC-1alpha) by phosphorylation | ||||
Axon guidance | ||||
DSCAM interactions | ||||
Developmental Biology | ||||
Immune System | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
platelet count | 2 | 3 | 4 | 97.7 | |||||
platelet crit | 2 | 3 | 4 | 97.7 | |||||
mitochondrial DNA measurement | 1 | 2 | 2 | 76.1 | |||||
eosinophil count | 2 | 1 | 2 | 68.3 | |||||
plasminogen activator inhibitor 1 measurement | 1 | 1 | 0 | 421.8 | 61.4 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
platelet count | 4 | 97.7 | |||||
platelet crit | 4 | 97.7 | |||||
mitochondrial DNA measurement | 2 | 76.1 | |||||
eosinophil count | 2 | 68.3 | |||||
plasminogen activator inhibitor 1 measurement | 0 | 421.8 | 61.4 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 12 | VGNC:12897 | 747077 | |||||
Macaque | mitogen-activated protein kinase 12 | 715745 | ||||||
Mouse | MGI:1353438 | 29857 | ||||||
Rat | RGD:70975 | 60352 | ||||||
Dog | mitogen-activated protein kinase 12 | VGNC:42993 | 607023 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | mitogen-activated protein kinase 12 | |||||
Macaque | mitogen-activated protein kinase 12 | |||||
Mouse | ||||||
Rat | ||||||
Dog | mitogen-activated protein kinase 12 | |||||
PMID | Year | Title |
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