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Tdark
ZNF75D
Zinc finger protein 75D

Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein that likely functions as a transcription factor. The protein, which belongs to the ZNF75 family, includes an N-terminal SCAN domain, a KRAB box, and five C2H2-type zinc finger motifs. Another functional gene belonging to this family is located on chromosome 16, while pseudogenes have been identified on chromosomes 11 and 12. Alternative splicing results in multiple transcripts variants. [provided by RefSeq, Jun 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370764
  • ENSP00000359800
  • ENSG00000186376
  • ENST00000370766
  • ENSP00000359802

Symbol
  • ZNF75
  • ZNF82
  • D8C6
  • ZNF75
  • ZNF82
  • ZSCAN28
  • ZKSCAN24
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
cell type or tissue
0.7
cell line
0.6
microRNA
0.58
tissue sample
0.57


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.96   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 105   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.96   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 105   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 75D
VGNC:1174
465873
Dog
zinc finger protein 75D
VGNC:54612
611850
Horse
zinc finger protein 75D
100063485
Pig
zinc finger protein 75D
100519584
Opossum
zinc finger protein 75a
100016724
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 75D
Dog
zinc finger protein 75D
Horse
zinc finger protein 75D
Pig
zinc finger protein 75D
Opossum
zinc finger protein 75a
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P51815-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (12)
1 – 10 of 12
TRIM28
Tbio
Family: Epigenetic
Novelty: 0.00778381
Score: 0.903
Data Source: STRINGDB
ZNF827
Tdark
Family: TF
Novelty: 0.22115243
Score: 0.568
Data Source: STRINGDB
KCTD5
Tbio
Novelty: 0.07740057
Score: 0.476
Data Source: STRINGDB
APMAP
Tbio
Novelty: 0.05926279
Score: 0.458
Data Source: STRINGDB
MAGEC3
Tdark
Novelty: 0.53505145
Score: 0.447
Data Source: STRINGDB
ZBTB21
Tbio
Family: TF
Novelty: 0.16032292
Score: 0.443
Data Source: STRINGDB
FOXRED1
Tbio
Family: Enzyme
Novelty: 0.07057772
Score: 0.438
Data Source: STRINGDB
TBC1D14
Tbio
Novelty: 0.25089884
Score: 0.428
Data Source: STRINGDB
KCNS1
Tclin
Family: IC
Novelty: 0.06465987
Score: 0.414
Data Source: STRINGDB
DNAJC16
Tdark
Novelty: 0.57359721
Score: 0.409
Data Source: STRINGDB
Publication Statistics
PubMed Score  2.96

PubMed score by year
PubTator Score  2.25

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer