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Tbio
ZNF41
Zinc finger protein 41

Protein Classes
Protein Summary
Description
May be involved in transcriptional regulation. This gene encodes a protein that contains KRAB-A and KRAB-B domains multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. An initial study suggested that this gene may be associated with X-linked cognitive disability, but a later study has called this finding into question (PMID:23871722).[provided by RefSeq, Apr 2016]
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.74
tissue sample
0.68
protein domain
0.58
cell line
0.44
microRNA
0.44


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.51   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 227   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.51   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 227   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 41
VGNC:14819
473590
Macaque
zinc finger protein 41
706770
Dog
zinc finger protein 41
VGNC:48721
480899
Horse
zinc finger protein 41
100060982
Cow
zinc finger protein 41
VGNC:37270
531674
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 41
Macaque
zinc finger protein 41
Dog
zinc finger protein 41
Horse
zinc finger protein 41
Cow
zinc finger protein 41
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P51814-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (34)
1 – 10 of 34
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.946
Data Source:  STRINGDB
ZNF385B
Tbio
Novelty:  0.14389498
Score:  0.8
Data Source:  STRINGDB
ARAF
Tchem
Family:  Kinase
Novelty:  0.00432488
Score:  0.78
Data Source:  STRINGDB
SLC9A7
Tbio
Family:  Transporter
Novelty:  0.03560989
Score:  0.638
Data Source:  STRINGDB
FTSJ1
Tbio
Family:  Enzyme
Novelty:  0.01511808
Score:  0.621
Data Source:  STRINGDB
ARHGEF6
Tbio
Novelty:  0.02162737
Score:  0.589
Data Source:  STRINGDB
TIMP1
Tbio
Family:  Enzyme
Novelty:  0.00020986
Score:  0.585
Data Source:  STRINGDB
CST8
Tbio
Novelty:  0.02316886
Score:  0.575
Data Source:  STRINGDB
SPIN3
Tchem
Novelty:  0.16670763
Score:  0.56
Data Source:  STRINGDB
CTSV
Tchem
Family:  Enzyme
Novelty:  0.00916301
Score:  0.551
Data Source:  STRINGDB
Publication Statistics
PubMed Score  5.51

PubMed score by year
PubTator Score  5.56

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer