Tbio ARSD Arylsulfatase D

Protein Summary

Description

The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y. [provided by RefSeq, Jul 2011]

Uniprot Accession IDs

• P51689
• Q9UHJ8
• ASD

Gene Name

• ARSD

Ensembl ID

• ENST00000381154
• ENSP00000370546
• ENSG00000006756

Symbol

• ASD

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
cellular component	0.76
cell type or tissue	0.7
tissue sample	0.63
microRNA	0.62
protein domain	0.58

Protein Classes

PANTHER Classes

Protein / Hydrolase / Arylsulfatase D

DTO Classes

Protein / Enzyme / Hydrolase / Arylsulfatase D

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 195.04   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 151   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 195.04   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 151   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0