HSD17B4
Peroxisomal multifunctional enzyme type 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
interacting protein | 1 | ||
disease perturbation | 0.99 | ||
protein domain | 0.92 | ||
kinase perturbation | 0.91 | ||
protein complex | 0.82 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Beta-oxidation of pristanoyl-CoA | ||||
Reactome | Beta-oxidation of very long chain fatty acids | ||||
Reactome | Bile acid and bile salt metabolism | ||||
Reactome | Fatty acid metabolism | ||||
Reactome | Metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Beta-oxidation of pristanoyl-CoA | ||||
Beta-oxidation of very long chain fatty acids | ||||
Bile acid and bile salt metabolism | ||||
Fatty acid metabolism | ||||
Metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 5 | 11 | 15 | 94.9 | |||||
waist-hip ratio | 4 | 11 | 13 | 94.9 | |||||
hip circumference | 1 | 9 | 9 | 92.1 | |||||
lymphocyte count | 2 | 2 | 2 | 92 | |||||
triglyceride measurement | 4 | 2 | 4 | 84.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 15 | 94.9 | |||||
waist-hip ratio | 13 | 94.9 | |||||
hip circumference | 9 | 92.1 | |||||
lymphocyte count | 2 | 92 | |||||
triglyceride measurement | 4 | 84.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | hydroxysteroid 17-beta dehydrogenase 4 | VGNC:13510 | 462019 | |||||
Macaque | hydroxysteroid 17-beta dehydrogenase 4 | 698369 | ||||||
Mouse | MGI:105089 | 15488 | ||||||
Rat | RGD:621806 | 79244 | ||||||
Dog | hydroxysteroid 17-beta dehydrogenase 4 | VGNC:41807 | 474630 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | hydroxysteroid 17-beta dehydrogenase 4 | |||||
Macaque | hydroxysteroid 17-beta dehydrogenase 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | hydroxysteroid 17-beta dehydrogenase 4 | |||||
PMID | Year | Title |
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