PDE6C
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
gene perturbation | 0.98 | ||
molecular function | 0.88 | ||
protein domain | 0.85 | ||
small molecule perturbation | 0.56 | ||
cell type or tissue | 0.52 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
KEGG | Metabolic pathways | ||||
KEGG | Purine metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolic pathways | ||||
Purine metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-EC | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 3 | 5 | 6 | 82.8 | |||||
waist-hip ratio | 3 | 5 | 6 | 80.9 | |||||
vitamin A measurement | 1 | 1 | 1 | 62.8 | |||||
waist circumference | 1 | 1 | 1 | 56.4 | |||||
BMI-adjusted waist circumference | 1 | 1 | 1 | 42.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
BMI-adjusted waist-hip ratio | 6 | 82.8 | |||||
waist-hip ratio | 6 | 80.9 | |||||
vitamin A measurement | 1 | 62.8 | |||||
waist circumference | 1 | 56.4 | |||||
BMI-adjusted waist circumference | 1 | 42.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | phosphodiesterase 6C | VGNC:7246 | 740456 | |||||
Macaque | phosphodiesterase 6C | 700261 | ||||||
Mouse | MGI:105956 | 110855 | ||||||
Rat | RGD:1309844 | 361752 | ||||||
Dog | phosphodiesterase 6C | VGNC:44359 | 486805 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | phosphodiesterase 6C | |||||
Macaque | phosphodiesterase 6C | |||||
Mouse | ||||||
Rat | ||||||
Dog | phosphodiesterase 6C | |||||
PMID | Year | Title |
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