Tbio RAB9A Ras-related protein Rab-9A

Protein Summary

Description

Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.

Uniprot Accession IDs

• P51151
• A8K390
• Q6ICN1

Gene Name

• RAB9A

Ensembl ID

• ENST00000464506
• ENSP00000420127
• ENSG00000123595
• ENST00000618931
• ENSP00000480777

Symbol

• RAB9
• RAB9

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.93
interacting protein	0.85
virus perturbation	0.72
cellular component	0.7
transcription factor perturbation	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.98   (req: < 5)

Gene RIFs: 25   (req: <= 3)

Antibodies: 246   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.98   (req: >= 5)

Gene RIFs: 25   (req: > 3)

Antibodies: 246   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0