FXR1
Fragile X mental retardation syndrome-related protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.97 | ||
virus perturbation | 0.96 | ||
kinase perturbation | 0.95 | ||
interacting protein | 0.9 | ||
transcription factor binding site profile | 0.77 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Disease | ||||
Reactome | Diseases of signal transduction | ||||
Reactome | Oncogenic MAPK signaling | ||||
Reactome | Signaling by BRAF and RAF fusions | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Disease | ||||
Diseases of signal transduction | ||||
Oncogenic MAPK signaling | ||||
Signaling by BRAF and RAF fusions | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
7 | 4 | 3 | 1.1 | 71.9 | |||||
self reported educational attainment | 2 | 2 | 2 | 68.4 | |||||
1 | 1 | 1 | 35 | ||||||
1 | 1 | 1 | 31.4 | ||||||
intelligence | 1 | 1 | 1 | 26.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
3 | 1.1 | 71.9 | |||||
self reported educational attainment | 2 | 68.4 | |||||
1 | 35 | ||||||
1 | 31.4 | ||||||
intelligence | 1 | 26.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | FMR1 autosomal homolog 1 | 746398 | ||||||
Macaque | FMR1 autosomal homolog 1 | 710170 | ||||||
Mouse | MGI:104860 | 14359 | ||||||
Dog | FMR1 autosomal homolog 1 | VGNC:53461 | 100855907 | |||||
Horse | FMR1 autosomal homolog 1 | 100066076 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | FMR1 autosomal homolog 1 | |||||
Macaque | FMR1 autosomal homolog 1 | |||||
Mouse | ||||||
Dog | FMR1 autosomal homolog 1 | |||||
Horse | FMR1 autosomal homolog 1 | |||||
PMID | Year | Title |
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