CRIP1
Cysteine-rich protein 1
Protein Summary
Seems to have a role in zinc absorption and may function as an intracellular zinc transport protein. Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]
- ENST00000330233
- ENSP00000332449
- ENSG00000213145
- ENST00000392531
- ENSP00000376315
- ENST00000409393
- ENSP00000386340
- CRIP
- CRP1
- CRHP
- CRIP
- CRP1
- CRP-1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
small molecule perturbation | 0.91 | ||
transcription factor perturbation | 0.91 | ||
gene perturbation | 0.9 | ||
PubMedID | 0.77 | ||
transcription factor binding site profile | 0.73 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 113.68 (req: < 5)
Gene RIFs: 12 (req: <= 3)
Antibodies: 117 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 113.68 (req: >= 5)
Gene RIFs: 12 (req: > 3)
Antibodies: 117 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 14
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0