CSNK1E
Casein kinase I isoform epsilon
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 0.99 | ||
kinase perturbation | 0.99 | ||
transcription factor perturbation | 0.88 | ||
small molecule | 0.85 | ||
PubMedID | 0.8 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | AURKA Activation by TPX2 | ||||
Reactome | Anchoring of the basal body to the plasma membrane | ||||
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle, Mitotic | ||||
Reactome | Centrosome maturation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
AURKA Activation by TPX2 | ||||
Anchoring of the basal body to the plasma membrane | ||||
Cell Cycle | ||||
Cell Cycle, Mitotic | ||||
Centrosome maturation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | WormBase | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
glomerular filtration rate | 4 | 5 | 4 | 6.3 | 93.2 | ||||
triglyceride measurement | 6 | 4 | 6 | 92.7 | |||||
serum alanine aminotransferase measurement | 2 | 2 | 1 | 6.9 | 80 | ||||
high density lipoprotein cholesterol measurement | 1 | 1 | 1 | 67.1 | |||||
body fat percentage | 2 | 2 | 3 | 66.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
glomerular filtration rate | 4 | 6.3 | 93.2 | ||||
triglyceride measurement | 6 | 92.7 | |||||
serum alanine aminotransferase measurement | 1 | 6.9 | 80 | ||||
high density lipoprotein cholesterol measurement | 1 | 67.1 | |||||
body fat percentage | 3 | 66.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | casein kinase 1 epsilon | VGNC:7338 | 458829 | |||||
Macaque | casein kinase 1, epsilon | 700565 | ||||||
Mouse | MGI:1351660 | 27373 | ||||||
Rat | RGD:62045 | 58822 | ||||||
Dog | casein kinase 1 epsilon | VGNC:54522 | 474510 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | casein kinase 1 epsilon | |||||
Macaque | casein kinase 1, epsilon | |||||
Mouse | ||||||
Rat | ||||||
Dog | casein kinase 1 epsilon | |||||
PMID | Year | Title |
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