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Tbio
SRP9
Signal recognition particle 9 kDa protein

Protein Summary
Description
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000304786
  • ENSP00000305230
  • ENSG00000143742
  • ENST00000366839
  • ENSP00000355804
  • ENST00000619790
  • ENSP00000485002

Symbol
  • ALURBP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
0.98
transcription factor binding site profile
0.95
kinase perturbation
0.93
transcription factor perturbation
0.84
disease perturbation
0.79


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GENEVA
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 49.36   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 49.36   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
signal recognition particle 9
VGNC:1567
736942
Macaque
signal recognition particle 9
700304
Mouse
MGI:1350930
27058
Rat
RGD:1597343
690345
Dog
signal recognition particle 9
VGNC:46810
611923
Species
Name
OMA
EggNOG
Inparanoid
Chimp
signal recognition particle 9
Macaque
signal recognition particle 9
Mouse
Rat
Dog
signal recognition particle 9
Protein Structure (6 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-P49458-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 5 of 6
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Pathways (5)
Metabolism of proteins (R-HSA-392499)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Metabolism of proteins
Reactome
SRP-dependent cotranslational protein targeting to membrane
Reactome
Translation
Name
Explore in Pharos
Explore in Source
Metabolism of proteins
SRP-dependent cotranslational protein targeting to membrane
Translation
Gene Ontology Terms (9)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
ProtInc
Traceable Author Statement (TAS)
ProtInc
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (192)
1 – 10 of 192
SRP54
Tbio
Novelty: 0.00535567
p_int: 0.999999932
p_ni: 6.8e-8
Score: 0.999
Data Source: BioPlex,STRINGDB
TRMT61A
Tbio
Family: Enzyme
Novelty: 0.04443394
p_int: 0.999998951
p_ni: 0.00000102
p_wrong: 2.9e-8
Score: 0.663
Data Source: BioPlex,STRINGDB
SRP68
Tbio
Novelty: 0.04666697
p_int: 0.999998249
p_ni: 0.000001751
Score: 0.999
Data Source: BioPlex,STRINGDB
SRP19
Tbio
Novelty: 0.01831843
p_int: 0.999998159
p_ni: 0.000001829
p_wrong: 1.2e-8
Score: 0.999
Data Source: BioPlex,STRINGDB
SRP14
Tbio
Novelty: 0.03745351
p_int: 0.999986306
p_ni: 0.000013694
Score: 0.999
Data Source: BioPlex,STRINGDB
SRP72
Tbio
Novelty: 0.03264445
p_int: 0.999976389
p_ni: 0.000023611
Score: 0.999
Data Source: BioPlex,STRINGDB
MTHFD2L
Tdark
Family: Enzyme
Novelty: 0.18530504
p_int: 0.998680253
p_ni: 0.000028084
p_wrong: 0.001291663
Score: 0.719
Data Source: BioPlex,STRINGDB
EDA
Tbio
Novelty: 0.00352464
p_int: 0.99721563
p_ni: 0.00278437
Data Source: BioPlex
MTHFD2
Tchem
Family: Enzyme
Novelty: 0.01776594
p_int: 0.992219216
p_ni: 0.007780784
Score: 0.768
Data Source: BioPlex,STRINGDB
TRMT6
Tbio
Family: Enzyme
Novelty: 0.06718902
p_int: 0.982502155
p_ni: 0.017497843
p_wrong: 2e-9
Score: 0.775
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  49.36

PubMed score by year
PubTator Score  35.13

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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