FNTB
Protein farnesyltransferase subunit beta
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
co-expressed gene | 1 | ||
transcription factor binding site profile | 0.94 | ||
ligand (protein) perturbation | 0.83 | ||
disease perturbation | 0.74 | ||
kinase perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | G alpha (i) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | Inactivation, recovery and regulation of the phototransduction cascade | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by GPCR | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
G alpha (i) signalling events | ||||
GPCR downstream signalling | ||||
Inactivation, recovery and regulation of the phototransduction cascade | ||||
Signal Transduction | ||||
Signaling by GPCR | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 4 | 3 | 4 | 98 | |||||
reticulocyte measurement | 3 | 2 | 3 | 90.2 | |||||
mean corpuscular volume | 2 | 3 | 3 | 89.9 | |||||
reticulocyte count | 2 | 2 | 2 | 86.6 | |||||
red blood cell density measurement | 1 | 1 | 1 | 82.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 4 | 98 | |||||
reticulocyte measurement | 3 | 90.2 | |||||
mean corpuscular volume | 3 | 89.9 | |||||
reticulocyte count | 2 | 86.6 | |||||
red blood cell density measurement | 1 | 82.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | farnesyltransferase, CAAX box, beta | 452971 | ||||||
Macaque | CHURC1-FNTB readthrough [Source:HGNC Symbol;Acc:HGNC:42960] | |||||||
Mouse | MGI:1861305 | 110606 | ||||||
Rat | RGD:620119 | 64511 | ||||||
Dog | farnesyltransferase, CAAX box, beta | 490735 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | farnesyltransferase, CAAX box, beta | |||||
Macaque | CHURC1-FNTB readthrough [Source:HGNC Symbol;Acc:HGNC:42960] | |||||
Mouse | ||||||
Rat | ||||||
Dog | farnesyltransferase, CAAX box, beta | |||||
PMID | Year | Title |
---|