Tbio TGM4 Protein-glutamine gamma-glutamyltransferase 4

Protein Summary

Description

Associated with the mammalian reproductive process. Catalyzes the cross-linking of proteins and the conjugation of polyamines to specific proteins in the seminal tract.

Uniprot Accession IDs

• P49221
• Q16707
• Q96QN4

Gene Name

• TGM4

Ensembl ID

• ENST00000296125
• ENSP00000296125
• ENSG00000163810
• ENST00000628744
• ENSP00000487307
• ENSG00000281886

Symbol

• TGP
• hTGP

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.92
microRNA	0.63
cell type or tissue	0.54
gene perturbation	0.5
cell line	0.49

Protein Classes

PANTHER Classes

Protein / Transferase / Acyltransferase / Protein-glutamine Gamma-glutamyltransferase 4

DTO Classes

Protein / Enzyme / Transferase / Acyltransferase / Protein-glutamine Gamma-glutamyltransferase 4

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.87   (req: < 5)

Gene RIFs: 13   (req: <= 3)

Antibodies: 301   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 89.87   (req: >= 5)

Gene RIFs: 13   (req: > 3)

Antibodies: 301   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0