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Tchem
NPY2R
Neuropeptide Y receptor type 2

Protein Summary
Description
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu-31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000329476
  • ENSP00000332591
  • ENSG00000185149
  • ENST00000506608
  • ENSP00000426366

Symbol
  • NPY2-R
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.94
phenotype
0.87
ligand (chemical)
0.82
kinase perturbation
0.71
cell type or tissue
0.7


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 67.26   (req: < 5)
Gene RIFs: 50   (req: <= 3)
Antibodies: 271   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 67.26   (req: >= 5)
Gene RIFs: 50   (req: > 3)
Antibodies: 271   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 25
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 293
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0