PITPNB
Phosphatidylinositol transfer protein beta isoform
Protein Summary
Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes. This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
- ENST00000320996
- ENSP00000321266
- ENSG00000180957
- ENST00000335272
- ENSP00000334738
- ENST00000634017
- ENSP00000487693
- VIB1B
- PtdInsTP
- PI-TP-beta
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 1 | ||
disease perturbation | 0.98 | ||
kinase perturbation | 0.96 | ||
histone modification site profile | 0.87 | ||
interacting protein | 0.86 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.02 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 249 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.02 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 249 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0