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Tbio
HSPA13
Heat shock 70 kDa protein 13

Protein Summary
Description
Has peptide-independent ATPase activity. The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The encoded protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000285667
  • ENSP00000285667
  • ENSG00000155304

Symbol
  • STCH
  • STCH
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.99
histone modification site profile
0.85
transcription factor binding site profile
0.81
molecular function
0.76
small molecule perturbation
0.72


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.47   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 175   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 27.47   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 175   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (155)
TNF
Tclin
Novelty:  0.00001457
p_int:  0.988975416
p_ni:  0.011024584
Score:  0.603
Data Source:  BioPlex,STRINGDB
DKKL1
Tbio
Novelty:  0.00544618
p_int:  0.988547107
p_ni:  0.011452893
Data Source:  BioPlex
B4GALT5
Tbio
Family:  Enzyme
Novelty:  0.04538678
p_int:  0.934275263
p_ni:  0.064366206
p_wrong:  0.001358532
Score:  0.709
Data Source:  BioPlex,STRINGDB
FBXO6
Tbio
Novelty:  0.02173918
p_int:  0.794373232
p_ni:  0.205626768
Score:  0.198
Data Source:  BioPlex,STRINGDB
HSPA12A
Tbio
Novelty:  0.11999085
Score:  0.974
Data Source:  STRINGDB
DNAJB1
Tbio
Novelty:  0.00139956
Score:  0.961
Data Source:  STRINGDB
DNAJC2
Tbio
Family:  TF
Novelty:  0.01515066
Score:  0.952
Data Source:  STRINGDB
DNAJB6
Tbio
Novelty:  0.01248367
Score:  0.951
Data Source:  STRINGDB
HSPA12B
Tbio
Novelty:  0.06444663
Score:  0.943
Data Source:  STRINGDB
DNAJC7
Tbio
Novelty:  0.02133191
Score:  0.942
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
Cellular response to heat stress (R-HSA-3371556)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cellular response to heat stress
Reactome
Cellular responses to external stimuli
Reactome
Cellular responses to stress
Reactome
Regulation of HSF1-mediated heat shock response
Name
Explore in Pharos
Explore in Source
Cellular response to heat stress
Cellular responses to external stimuli
Cellular responses to stress
Regulation of HSF1-mediated heat shock response
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (21)
Find Similar Targets
Items per page:
10
1 – 7 of 7
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
heat shock protein family A (Hsp70) member 13
VGNC:6439
474070
Macaque
heat shock protein family A (Hsp70) member 13
694660
Mouse
MGI:1309463
110920
Rat
RGD:3775
29734
Dog
heat shock protein family A (Hsp70) member 13
VGNC:53026
608091
Species
Name
OMA
EggNOG
Inparanoid
Chimp
heat shock protein family A (Hsp70) member 13
Macaque
heat shock protein family A (Hsp70) member 13
Mouse
Rat
Dog
heat shock protein family A (Hsp70) member 13
Publication Statistics
PubMed Score 27.47
PubMed score by year
PubTator Score 7.77
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title