You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
TRAPPC10
Trafficking protein particle complex subunit 10

Protein Summary
Description
May play a role in vesicular transport from endoplasmic reticulum to Golgi. The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000291574
  • ENSP00000291574
  • ENSG00000160218
  • ENST00000380221
  • ENSP00000369570

Symbol
  • EHOC1
  • TMEM1
  • EHOC1
  • GT334
  • TMEM1
  • TRS30
  • EHOC-1
  • TRS130
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.79
microRNA
0.75
transcription factor binding site profile
0.7
virus perturbation
0.68
cell type or tissue
0.66


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.49   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 128   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.49   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 128   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
trafficking protein particle complex 10
VGNC:14684
458596
Macaque
trafficking protein particle complex 10
713177
Mouse
MGI:1336209
216131
Rat
RGD:1311263
309678
Dog
trafficking protein particle complex 10
487789
Species
Name
OMA
EggNOG
Inparanoid
Chimp
trafficking protein particle complex 10
Macaque
trafficking protein particle complex 10
Mouse
Rat
Dog
trafficking protein particle complex 10
Pathways (10)
Asparagine N-linked glycosylation (R-HSA-446203)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 10
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Asparagine N-linked glycosylation
Reactome
COPII-mediated vesicle transport
Reactome
ER to Golgi Anterograde Transport
Reactome
Membrane Trafficking
Reactome
Metabolism of proteins
Name
Explore in Pharos
Explore in Source
Asparagine N-linked glycosylation
COPII-mediated vesicle transport
ER to Golgi Anterograde Transport
Membrane Trafficking
Metabolism of proteins
Gene Ontology Terms (9)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (122)
1 – 10 of 122
TRAPPC5
Tdark
Novelty: 0.22558077
p_int: 0.999999314
p_ni: 6.86e-7
Score: 0.998
Data Source: BioPlex,STRINGDB
TRAPPC2
Tbio
Novelty: 0.02016231
p_int: 0.999998201
p_ni: 0.000001799
Score: 0.997
Data Source: BioPlex,STRINGDB
TRAPPC1
Tbio
Novelty: 0.09781468
p_int: 0.999989639
p_ni: 0.000010361
Score: 0.998
Data Source: BioPlex,STRINGDB
STMN4
Tbio
Novelty: 0.00422625
p_int: 0.999938244
p_ni: 0.000061756
Score: 0.741
Data Source: BioPlex,STRINGDB
BCL2L14
Tbio
Novelty: 0.03980069
p_int: 0.999904502
p_ni: 0.000095498
Score: 0.745
Data Source: BioPlex,STRINGDB
KANK4
Tdark
Novelty: 0.22871735
p_int: 0.999897787
p_ni: 0.000102213
Score: 0.741
Data Source: BioPlex,STRINGDB
GLB1
Tchem
Family: Enzyme
Novelty: 0.00241713
p_int: 0.99987391
p_ni: 0.00012609
Score: 0.671
Data Source: BioPlex,STRINGDB
CABS1
Tbio
Novelty: 0.10451682
p_int: 0.999801696
p_ni: 0.000198304
Score: 0.816
Data Source: BioPlex,STRINGDB
GATA2
Tbio
Family: TF
Novelty: 0.00153967
p_int: 0.999456585
p_ni: 0.000543415
Score: 0.189
Data Source: BioPlex,STRINGDB
RAB43
Tbio
Family: Enzyme
Novelty: 0.07527576
p_int: 0.998851665
p_ni: 0.001148334
Score: 0.376
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  19.49

PubMed score by year
PubTator Score  9.97

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: