KCNJ3
G protein-activated inward rectifier potassium channel 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.9 | ||
disease perturbation | 0.68 | ||
PubMedID | 0.66 | ||
disease | 0.63 | ||
microRNA | 0.59 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of G protein gated Potassium channels | ||||
Reactome | Activation of GABAB receptors | ||||
Reactome | G protein gated Potassium channels | ||||
Reactome | GABA B receptor activation | ||||
Reactome | GABA receptor activation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of G protein gated Potassium channels | ||||
Activation of GABAB receptors | ||||
G protein gated Potassium channels | ||||
GABA B receptor activation | ||||
GABA receptor activation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred by Curator (IC) | BHF-UCL | |||
Inferred by Curator (IC) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 4 | 4 | 3 | 5.8 | 81.3 | ||||
smoking status measurement | 2 | 1 | 2 | 73 | |||||
intelligence | 5 | 7 | 2 | 5.9 | 73 | ||||
mean platelet volume | 2 | 1 | 2 | 68.6 | |||||
smoking initiation | 2 | 2 | 2 | 44 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 3 | 5.8 | 81.3 | ||||
smoking status measurement | 2 | 73 | |||||
intelligence | 2 | 5.9 | 73 | ||||
mean platelet volume | 2 | 68.6 | |||||
smoking initiation | 2 | 44 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | potassium voltage-gated channel subfamily J member 3 | VGNC:8360 | 737029 | |||||
Macaque | potassium voltage-gated channel subfamily J member 3 | 696473 | ||||||
Mouse | MGI:104742 | 16519 | ||||||
Rat | RGD:2958 | 50599 | ||||||
Dog | potassium voltage-gated channel subfamily J member 3 | VGNC:42264 | 488355 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | potassium voltage-gated channel subfamily J member 3 | |||||
Macaque | potassium voltage-gated channel subfamily J member 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | potassium voltage-gated channel subfamily J member 3 | |||||
PMID | Text |
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