CXCL12
Stromal cell-derived factor 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
biological term | 1 | ||
PubMedID | 1 | ||
disease perturbation | 0.9 | ||
disease | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Chemokine receptors bind chemokines | ||||
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | Developmental Biology | ||||
Reactome | ESR-mediated signaling | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Chemokine receptors bind chemokines | ||||
Class A/1 (Rhodopsin-like receptors) | ||||
Developmental Biology | ||||
ESR-mediated signaling | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
5 | 5 | 2 | 1.1 | 90.9 | |||||
neutrophil count | 2 | 2 | 2 | 87.6 | |||||
myeloid white cell count | 1 | 1 | 1 | 82 | |||||
lymphocyte count | 2 | 3 | 3 | 80.4 | |||||
leukocyte count | 1 | 1 | 1 | 77.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
2 | 1.1 | 90.9 | |||||
neutrophil count | 2 | 87.6 | |||||
myeloid white cell count | 1 | 82 | |||||
lymphocyte count | 3 | 80.4 | |||||
leukocyte count | 1 | 77.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Mouse | MGI:103556 | 20315 | ||||||
Rat | RGD:3651 | 24772 | ||||||
Horse | C-X-C motif chemokine ligand 12 | VGNC:16983 | 100049872 | |||||
Cow | C-X-C motif chemokine ligand 12 | VGNC:27848 | 613811 | |||||
Pig | C-X-C motif chemokine ligand 12 | 494460 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Mouse | ||||||
Rat | ||||||
Horse | C-X-C motif chemokine ligand 12 | |||||
Cow | C-X-C motif chemokine ligand 12 | |||||
Pig | C-X-C motif chemokine ligand 12 | |||||
PMID | Year | Title |
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