You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
CSN1S1
Alpha-S1-casein

Protein Classes
Protein Summary
Description
Important role in the capacity of milk to transport calcium phosphate. Casoxin D acts as opioid antagonist and has vasorelaxing activity mediated by bradykinin B1 receptors.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000246891
  • ENSP00000246891
  • ENSG00000126545
  • ENST00000507763
  • ENSP00000422611

Symbol
  • CASA
  • CSN1
  • CASA
  • CSN1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.73
tissue
0.59
virus perturbation
0.55
cell line
0.51
disease
0.5


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 504.12   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 161   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 504.12   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 161   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
casein alpha s1
VGNC:583
461283
Dog
casein alpha s1
VGNC:39664
611749
Horse
casein alpha s1
VGNC:16905
100033982
Cow
casein alpha s1
VGNC:27763
282208
Pig
casein alpha s1
445514
Species
Name
OMA
EggNOG
Inparanoid
Chimp
casein alpha s1
Dog
casein alpha s1
Horse
casein alpha s1
Cow
casein alpha s1
Pig
casein alpha s1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P47710-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (7)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (39)
1 – 10 of 39
PDE10A
Tclin
Family: Enzyme
Novelty: 0.00318215
p_int: 0.999108752
p_ni: 8.3e-8
p_wrong: 0.000891166
Score: 0.379
Data Source: BioPlex,STRINGDB
B4GALNT4
Tdark
Family: Enzyme
Novelty: 0.19278471
p_int: 0.998772617
p_ni: 0.000704747
p_wrong: 0.000522636
Score: 0.187
Data Source: BioPlex,STRINGDB
LTBP1
Tbio
Novelty: 0.00958396
p_int: 0.998120733
p_ni: 0.001879218
p_wrong: 4.9e-8
Data Source: BioPlex
EMILIN3
Tbio
Novelty: 0.4
p_int: 0.986296063
p_ni: 0.013703937
Score: 0.188
Data Source: BioPlex,STRINGDB
KLHL15
Tbio
Novelty: 0.54712519
p_int: 0.972287605
p_ni: 0.027712395
Data Source: BioPlex
HSPA5
Tchem
Novelty: 0.00043424
p_int: 0.949170596
p_ni: 0.050829404
Score: 0.172
Data Source: BioPlex,STRINGDB
TIMP3
Tbio
Family: Enzyme
Novelty: 0.00134742
p_int: 0.938758385
p_ni: 0.042272536
p_wrong: 0.018969079
Data Source: BioPlex
ERF
Tbio
Family: TF
Novelty: 0.00182385
p_int: 0.938707298
p_ni: 0.061292658
p_wrong: 4.4e-8
Score: 0.183
Data Source: BioPlex,STRINGDB
BCOR
Tbio
Novelty: 0.05718292
p_int: 0.9359546
p_ni: 0.0640454
Data Source: BioPlex
CDKN2AIP
Tbio
Novelty: 0.15331029
p_int: 0.91623756
p_ni: 0.083680652
p_wrong: 0.000081788
Data Source: BioPlex
Publication Statistics
PubMed Score  504.12

PubMed score by year
PubTator Score  759.59

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer