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Tbio
MAGEA9
Melanoma-associated antigen 9

Protein Summary
Description
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression. This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000243314
  • ENSP00000243314
  • ENSG00000123584
  • ENST00000595065
  • ENSP00000471017
  • ENSG00000267978

Symbol
  • MAGE9
  • MAGEA9A
  • CT1.9
  • MAGE9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.63
disease
0.48
tissue sample
0.32
interacting protein
0.31
tissue
0.31


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.47   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 271   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.47   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 271   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
MAGE family member A9
701723
Species
Name
OMA
EggNOG
Inparanoid
Macaque
MAGE family member A9
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P43362-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (23)
1 – 10 of 23
MAGEA10
Tbio
Novelty: 0.05364393
p_int: 0.999999964
p_ni: 2e-8
p_wrong: 1.6e-8
Data Source: BioPlex
MAGEA4
Tbio
Novelty: 0.00949096
p_int: 0.999999603
p_ni: 4e-9
p_wrong: 3.93e-7
Data Source: BioPlex
MAGEA1
Tbio
Novelty: 0.00506874
p_int: 0.999996987
p_ni: 0.000003013
Score: 0.195
Data Source: BioPlex,STRINGDB
NSA2
Tbio
Novelty: 0.04542275
p_int: 0.98390143
p_ni: 0.01609857
Data Source: BioPlex
CTAG2
Tbio
Novelty: 0.02983879
Score: 0.608
Data Source: STRINGDB
CTAG1A
Tbio
Novelty: 0.00345306
Score: 0.587
Data Source: STRINGDB
GAGE12B
Tdark
Novelty: 5.71932986
Score: 0.501
Data Source: STRINGDB
TP53
Tchem
Family: TF
Novelty: 0.00001907
Score: 0.497
Data Source: STRINGDB
PRAME
Tbio
Novelty: 0.00543263
Score: 0.492
Data Source: STRINGDB
TMEM86A
Tdark
Family: Enzyme
Novelty: 1.07989252
Score: 0.462
Data Source: STRINGDB
Publication Statistics
PubMed Score  11.47

PubMed score by year
PubTator Score  27.56

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer