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Tbio
ETV4
ETS translocation variant 4

Protein Summary
Description
Transcriptional activator that binds to the enhancer of the adenovirus E1A gene; the core-binding sequence is 5'[AC]GGA[AT]GT-3'.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000319349
  • ENSP00000321835
  • ENSG00000175832
  • ENST00000393664
  • ENSP00000377273
  • ENST00000538265
  • ENSP00000443846
  • ENST00000545954
  • ENSP00000440023
  • ENST00000586826
  • ENSP00000468636
  • ENST00000591713
  • ENSP00000465718

Symbol
  • E1AF
  • PEA3
  • E1AF
  • PEA3
  • E1A-F
  • PEAS3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
0.97
gene perturbation
0.9
kinase perturbation
0.88
transcription factor binding site profile
0.8
molecular function
0.79


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 329.92   (req: < 5)
Gene RIFs: 98   (req: <= 3)
Antibodies: 263   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 329.92   (req: >= 5)
Gene RIFs: 98   (req: > 3)
Antibodies: 263   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0