PAFAH1B1
Platelet-activating factor acetylhydrolase IB subunit alpha
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
transcription factor perturbation | 1 | ||
disease perturbation | 0.99 | ||
virus perturbation | 0.94 | ||
protein domain | 0.92 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | AURKA Activation by TPX2 | ||||
Reactome | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Reactome | Amplification of signal from the kinetochores | ||||
Reactome | Anchoring of the basal body to the plasma membrane | ||||
Reactome | COPI-independent Golgi-to-ER retrograde traffic | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
AURKA Activation by TPX2 | ||||
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Amplification of signal from the kinetochores | ||||
Anchoring of the basal body to the plasma membrane | ||||
COPI-independent Golgi-to-ER retrograde traffic | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neuroticism measurement | 4 | 7 | 3 | 6.1 | 71.6 | ||||
wellbeing measurement | 2 | 3 | 3 | 64.3 | |||||
mean platelet volume | 2 | 2 | 2 | 63 | |||||
alkaline phosphatase measurement | 1 | 1 | 1 | 59.8 | |||||
depressive symptom measurement | 1 | 2 | 2 | 58.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neuroticism measurement | 3 | 6.1 | 71.6 | ||||
wellbeing measurement | 3 | 64.3 | |||||
mean platelet volume | 2 | 63 | |||||
alkaline phosphatase measurement | 1 | 59.8 | |||||
depressive symptom measurement | 2 | 58.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | platelet activating factor acetylhydrolase 1b regulatory subunit 1 | VGNC:9502 | 454422 | |||||
Macaque | platelet activating factor acetylhydrolase 1b regulatory subunit 1 | 574255 | ||||||
Mouse | MGI:109520 | 18472 | ||||||
Rat | RGD:620331 | 83572 | ||||||
Dog | platelet activating factor acetylhydrolase 1b regulatory subunit 1 | VGNC:44239 | 480656 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | platelet activating factor acetylhydrolase 1b regulatory subunit 1 | |||||
Macaque | platelet activating factor acetylhydrolase 1b regulatory subunit 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | platelet activating factor acetylhydrolase 1b regulatory subunit 1 | |||||
PMID | Year | Title |
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