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Tdark
RBM34
RNA-binding protein 34

Protein Summary
Description
This gene encodes a member of the RNA-binding motif family of RNA recognition motif proteins. The encoded protein contains an RNA-binding domain made up of two RNA recognition motif subdomains referred to as RNA recognition motif-1 and RNA recognition motif-2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000408888
  • ENSP00000386226
  • ENSG00000188739

Symbol
  • KIAA0117
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.9
interacting protein
0.87
transcription factor binding site profile
0.86
microRNA
0.66
tissue sample
0.66


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.43   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 104   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.43   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 104   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
1
1
1
68.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
1
68.3
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 34
VGNC:1483
107970653
Mouse
MGI:1098653
52202
Rat
RGD:1310161
307956
Dog
RNA binding motif protein 34
VGNC:45419
479199
Horse
RNA binding motif protein 34
VGNC:22242
100146167
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 34
Mouse
Rat
Dog
RNA binding motif protein 34
Horse
RNA binding motif protein 34
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P42696-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Protein-Protein Interactions (270)
1 – 10 of 270
HIST2H2BF
Tdark
Novelty:  1.40321359
p_int:  0.999998581
p_ni:  7e-9
p_wrong:  0.000001412
Score:  0.187
Data Source:  BioPlex,STRINGDB
CENPI
Tbio
Novelty:  0.01938121
p_int:  0.999795869
p_ni:  0.000204131
Score:  0.228
Data Source:  BioPlex,STRINGDB
CENPC
Tbio
Novelty:  0.00638662
p_int:  0.999439341
p_ni:  0.000560652
p_wrong:  7e-9
Score:  0.268
Data Source:  BioPlex,STRINGDB
RPL36AL
Tbio
Novelty:  0.09336423
p_int:  0.999190233
p_ni:  0.000809734
p_wrong:  3.3e-8
Score:  0.225
Data Source:  BioPlex,STRINGDB
SDAD1
Tdark
Novelty:  0.2574139
p_int:  0.998287655
p_ni:  0.001712345
Score:  0.882
Data Source:  BioPlex,STRINGDB
PUM3
Tbio
Novelty:  0.02344206
p_int:  0.996644852
p_ni:  0.003355148
Score:  0.95
Data Source:  BioPlex,STRINGDB
TAF1D
Tdark
Family:  Enzyme
Novelty:  0.26072519
p_int:  0.995925896
p_ni:  0.004074101
p_wrong:  3e-9
Score:  0.554
Data Source:  BioPlex,STRINGDB
RRP8
Tbio
Family:  Enzyme
Novelty:  0.04922797
p_int:  0.995448092
p_ni:  0.004551908
Score:  0.781
Data Source:  BioPlex,STRINGDB
RPL26L1
Tdark
Novelty:  0.75408617
p_int:  0.993929147
p_ni:  0.006070853
Score:  0.397
Data Source:  BioPlex,STRINGDB
RPL30
Tbio
Novelty:  0.0134194
p_int:  0.992378604
p_ni:  0.007621396
Score:  0.532
Data Source:  BioPlex,STRINGDB
Publication Statistics
PubMed Score  1.43

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer