ABL2
Tyrosine-protein kinase ABL2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
drug perturbation | 0.99 | ||
molecular function | 0.99 | ||
protein domain | 0.99 | ||
kinase perturbation | 0.97 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Developmental Biology | ||||
Reactome | Role of ABL in ROBO-SLIT signaling | ||||
Reactome | Signaling by ROBO receptors | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Developmental Biology | ||||
Role of ABL in ROBO-SLIT signaling | ||||
Signaling by ROBO receptors | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | CAFA | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
testosterone measurement | 3 | 2 | 3 | 93.7 | |||||
1 | 1 | 1 | 2.3 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
testosterone measurement | 3 | 93.7 | |||||
1 | 2.3 | ||||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | ABL proto-oncogene 2, non-receptor tyrosine kinase | VGNC:12980 | 457552 | |||||
Macaque | ABL proto-oncogene 2, non-receptor tyrosine kinase | 717037 | ||||||
Mouse | MGI:87860 | 11352 | ||||||
Rat | RGD:1590898 | 304883 | ||||||
Dog | ABL proto-oncogene 2, non-receptor tyrosine kinase | VGNC:53323 | 480052 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | ABL proto-oncogene 2, non-receptor tyrosine kinase | |||||
Macaque | ABL proto-oncogene 2, non-receptor tyrosine kinase | |||||
Mouse | ||||||
Rat | ||||||
Dog | ABL proto-oncogene 2, non-receptor tyrosine kinase | |||||
PMID | Year | Title |
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