Tbio BUD31 Protein BUD31 homolog

Protein Summary

Description

Involved in the pre-mRNA splicing process (PubMed:28502770, PubMed:28076346). May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity (PubMed:25091737).

Uniprot Accession IDs

• P41223
• A4D274
• B7Z4S9
• D6W5S6
• Q6IB53
• Q9UDV1

Gene Name

• BUD31

Ensembl ID

• ENST00000222969
• ENSP00000222969
• ENSG00000106245
• ENST00000403633
• ENSP00000386023

Symbol

• EDG2
• G10
• EDG2
• Cwc14
• EDG-2
• fSAP17
• YCR063W

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.96
histone modification site profile	0.87
transcription factor binding site profile	0.76
virus perturbation	0.76
co-expressed gene	0.72

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Zinc Finger Transcription Factor / Protein Bud31 Homolog

DTO Classes

Protein / Transcription Factor / Zinc Finger Transcription Factor / Protein Bud31 Homolog

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.46   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 219   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.46   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 219   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0