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Tbio
ETV5
ETS translocation variant 5

Protein Summary
Description
Binds to DNA sequences containing the consensus nucleotide core sequence 5'-GGAA.-3'.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306376
  • ENSP00000306894
  • ENSG00000244405
  • ENST00000434744
  • ENSP00000413755

Symbol
  • ERM
  • ERM
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.99
PubMedID
0.98
transcription factor perturbation
0.94
transcription factor binding site profile
0.9
biological process
0.87


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2011.76   (req: < 5)
Gene RIFs: 36   (req: <= 3)
Antibodies: 311   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2011.76   (req: >= 5)
Gene RIFs: 36   (req: > 3)
Antibodies: 311   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 18
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (68)
DET1
Tbio
Novelty:  0.01138079
p_int:  0.999997975
p_ni:  0.000002025
Score:  0.865
Data Source:  BioPlex,STRINGDB
COP1
Tbio
Family:  Enzyme
Novelty:  0.10908534
p_int:  0.999994048
p_ni:  0.000005951
Score:  0.852
Data Source:  BioPlex,STRINGDB
STK40
Tbio
Family:  Kinase
Novelty:  0.10461675
p_int:  0.999992285
p_ni:  0.000007712
p_wrong:  4e-9
Score:  0.823
Data Source:  BioPlex,STRINGDB
UBE2E3
Tbio
Novelty:  0.03477232
p_int:  0.975640662
p_ni:  0.012132018
p_wrong:  0.01222732
Score:  0.731
Data Source:  BioPlex,STRINGDB
JUN
Tchem
Family:  TF
Novelty:  0.00006856
Score:  0.937
Data Source:  STRINGDB
CCR5
Tclin
Family:  GPCR
Novelty:  0.00022549
Score:  0.906
Data Source:  STRINGDB
IL18R1
Tbio
Novelty:  0.01634385
Score:  0.905
Data Source:  STRINGDB
IFNG
Tclin
Novelty:  0.00009731
Score:  0.903
Data Source:  STRINGDB
ROCK2
Tclin
Family:  Kinase
Novelty:  0.00242311
Score:  0.903
Data Source:  STRINGDB
STAT4
Tchem
Family:  TF
Novelty:  0.00251747
Score:  0.902
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (21)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from Mutant Phenotype (IMP)
NTNU_SB
Inferred from Mutant Phenotype (IMP)
NTNU_SB
Inferred from Sequence Alignment (ISA)
NTNU_SB
Traceable Author Statement (TAS)
ProtInc
Disease Associations ()
No disease associations found
GWAS Traits (22)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
18
5
28
2.8
97.5
high density lipoprotein cholesterol measurement
6
6
8
94.3
glomerular filtration rate
5
5
5
93.2
physical activity measurement
1
2
4
80.3
body height
1
1
1
76.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
28
2.8
97.5
high density lipoprotein cholesterol measurement
8
94.3
glomerular filtration rate
5
93.2
physical activity measurement
4
80.3
body height
1
76.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (14)
1 – 5 of 14
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ETS variant 5
VGNC:1811
460906
Macaque
ETS variant 5
700907
Mouse
MGI:1096867
104156
Rat
RGD:1309590
303828
Dog
ETS variant 5
VGNC:40499
607474
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ETS variant 5
Macaque
ETS variant 5
Mouse
Rat
Dog
ETS variant 5
Publication Statistics
PubMed Score 2011.76
PubMed score by year
PubTator Score 46.80
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title