ADH7
Alcohol dehydrogenase class 4 mu/sigma chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.95 | ||
protein domain | 0.92 | ||
disease perturbation | 0.79 | ||
pathway | 0.75 | ||
kinase perturbation | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Biological oxidations | ||||
Reactome | Ethanol oxidation | ||||
Reactome | Metabolism | ||||
Reactome | Phase I - Functionalization of compounds | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Biological oxidations | ||||
Ethanol oxidation | ||||
Metabolism | ||||
Phase I - Functionalization of compounds | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
alcohol consumption measurement | 14 | 18 | 32 | 9.2 | 99.9 | ||||
alcohol use disorder measurement | 6 | 5 | 3 | 7.2 | 98.8 | ||||
6 | 6 | 0 | 1.8 | 98.8 | |||||
alcohol dependence measurement | 2 | 6 | 7 | 97.4 | |||||
IGF-1 measurement | 1 | 2 | 2 | 90.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
alcohol consumption measurement | 32 | 9.2 | 99.9 | ||||
alcohol use disorder measurement | 3 | 7.2 | 98.8 | ||||
0 | 1.8 | 98.8 | |||||
alcohol dependence measurement | 7 | 97.4 | |||||
IGF-1 measurement | 2 | 90.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 708520 | ||||||
Mouse | MGI:87926 | 11529 | ||||||
Rat | RGD:621638 | 171178 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | |||||
Mouse | ||||||
Rat | ||||||
PMID | Year | Title |
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