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Tbio
TXLNA
Alpha-taxilin

Protein Summary
Description
May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000373609
  • ENSP00000362711
  • ENSG00000084652
  • ENST00000373610
  • ENSP00000362712

Symbol
  • TXLN
  • IL14
  • TXLN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.87
transcription factor binding site profile
0.78
co-expressed gene
0.76
microRNA
0.76
drug perturbation
0.71


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.08   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 138   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 37.08   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 138   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (77)
TXLNG
Tbio
Novelty:  0.08274423
p_int:  0.999999394
p_ni:  6.06e-7
Score:  0.879
Data Source:  BioPlex,STRINGDB
ARHGEF12
Tchem
Novelty:  0.01365866
p_int:  0.999997637
p_ni:  0.000002363
Data Source:  BioPlex
TXLNB
Tbio
Novelty:  0.12751933
p_int:  0.99999707
p_ni:  5.35e-7
p_wrong:  0.000002396
Score:  0.868
Data Source:  BioPlex,STRINGDB
ZNF426
Tdark
Family:  TF
Novelty:  0.19450662
p_int:  0.999996948
p_ni:  0.000003052
Data Source:  BioPlex
ATRIP
Tbio
Novelty:  0.01415267
p_int:  0.99998523
p_ni:  0.000014396
p_wrong:  3.74e-7
Data Source:  BioPlex
TBK1
Tchem
Family:  Kinase
Novelty:  0.00194753
p_int:  0.99994427
p_ni:  0.000055731
Score:  0.693
Data Source:  BioPlex,STRINGDB
CCDC138
Tdark
Novelty:  4.02014418
p_int:  0.999940111
p_ni:  0.000059888
p_wrong:  1e-9
Data Source:  BioPlex
CPNE2
Tdark
Novelty:  0.24188419
p_int:  0.999918086
p_ni:  0.000081914
Data Source:  BioPlex
C1orf122
Tdark
Novelty:  11.73333333
p_int:  0.999769692
p_ni:  0.000197145
p_wrong:  0.000033164
Score:  0.656
Data Source:  BioPlex,STRINGDB
WHAMM
Tbio
Novelty:  0.06965013
p_int:  0.999748137
p_ni:  0.000007148
p_wrong:  0.000244716
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (12)
Cytokine Signaling in Immune system (R-HSA-1280215)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Cytokine Signaling in Immune system
Reactome
Immune System
Reactome
Other interleukin signaling
Reactome
Signaling by Interleukins
Name
Explore in Pharos
Explore in Source
Cytokine Signaling in Immune system
Immune System
Other interleukin signaling
Signaling by Interleukins
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep duration
1
1
0
3.8
17.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
sleep duration
0
3.8
17.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
taxilin alpha
VGNC:14294
100614679
Macaque
taxilin alpha
707704
Mouse
MGI:105968
109658
Rat
RGD:1583435
682457
Dog
taxilin alpha
VGNC:48006
487313
Species
Name
OMA
EggNOG
Inparanoid
Chimp
taxilin alpha
Macaque
taxilin alpha
Mouse
Rat
Dog
taxilin alpha
Publication Statistics
PubMed Score 37.08
PubMed score by year
PubTator Score 13.16
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title