COL18A1
Collagen alpha-1(XVIII) chain
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.99 | ||
transcription factor perturbation | 0.98 | ||
PubMedID | 0.97 | ||
disease perturbation | 0.95 | ||
biological term | 0.89 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of Matrix Metalloproteinases | ||||
Reactome | Assembly of collagen fibrils and other multimeric structures | ||||
Reactome | Collagen biosynthesis and modifying enzymes | ||||
Reactome | Collagen chain trimerization | ||||
Reactome | Collagen degradation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of Matrix Metalloproteinases | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
Collagen biosynthesis and modifying enzymes | ||||
Collagen chain trimerization | ||||
Collagen degradation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
triglyceride measurement | 2 | 1 | 3 | 78.9 | |||||
BMI-adjusted waist-hip ratio | 2 | 4 | 4 | 77.1 | |||||
waist-hip ratio | 1 | 3 | 3 | 72.5 | |||||
apolipoprotein A 1 measurement | 2 | 2 | 2 | 71.4 | |||||
waist circumference | 1 | 2 | 2 | 51.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
triglyceride measurement | 3 | 78.9 | |||||
BMI-adjusted waist-hip ratio | 4 | 77.1 | |||||
waist-hip ratio | 3 | 72.5 | |||||
apolipoprotein A 1 measurement | 2 | 71.4 | |||||
waist circumference | 2 | 51.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | collagen type XVIII alpha 1 chain | VGNC:10689 | 474050 | |||||
Mouse | MGI:88451 | 12822 | ||||||
Rat | RGD:70936 | 85251 | ||||||
Dog | collagen type XVIII alpha 1 chain | VGNC:49781 | 100687767 | |||||
Horse | collagen type XVIII alpha 1 chain | VGNC:16728 | 100055712 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | collagen type XVIII alpha 1 chain | |||||
Mouse | ||||||
Rat | ||||||
Dog | collagen type XVIII alpha 1 chain | |||||
Horse | collagen type XVIII alpha 1 chain | |||||
PMID | Year | Title |
---|