COL15A1
Collagen alpha-1(XV) chain
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.85 | ||
gene perturbation | 0.81 | ||
PubMedID | 0.81 | ||
small molecule perturbation | 0.65 | ||
cell line | 0.61 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Assembly of collagen fibrils and other multimeric structures | ||||
Reactome | Collagen biosynthesis and modifying enzymes | ||||
Reactome | Collagen chain trimerization | ||||
Reactome | Collagen degradation | ||||
Reactome | Collagen formation | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Assembly of collagen fibrils and other multimeric structures | ||||
Collagen biosynthesis and modifying enzymes | ||||
Collagen chain trimerization | ||||
Collagen degradation | ||||
Collagen formation | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
pulse pressure measurement | 1 | 1 | 1 | 75.9 | |||||
BMI-adjusted waist circumference | 1 | 3 | 3 | 67.8 | |||||
2 | 2 | 0 | 1.1 | 60.4 | |||||
2 | 2 | 0 | 1.1 | 51.4 | |||||
waist-hip ratio | 1 | 1 | 1 | 42.3 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
pulse pressure measurement | 1 | 75.9 | |||||
BMI-adjusted waist circumference | 3 | 67.8 | |||||
0 | 1.1 | 60.4 | |||||
0 | 1.1 | 51.4 | |||||
waist-hip ratio | 1 | 42.3 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | collagen type XV alpha 1 chain | VGNC:10680 | 464611 | |||||
Macaque | collagen type XV alpha 1 chain | 715003 | ||||||
Mouse | MGI:88449 | 12819 | ||||||
Rat | RGD:1310820 | 298069 | ||||||
Dog | collagen type XV alpha 1 chain | VGNC:39460 | 474778 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | collagen type XV alpha 1 chain | |||||
Macaque | collagen type XV alpha 1 chain | |||||
Mouse | ||||||
Rat | ||||||
Dog | collagen type XV alpha 1 chain | |||||
PMID | Year | Title |
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