ACVRL1
Serine/threonine-protein kinase receptor R3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
molecular function | 1 | ||
protein domain | 0.92 | ||
disease perturbation | 0.79 | ||
biological term | 0.78 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Signal Transduction | ||||
Reactome | Signaling by BMP | ||||
Reactome | Signaling by TGF-beta family members | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Signal Transduction | ||||
Signaling by BMP | ||||
Signaling by TGF-beta family members | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neutrophil count | 3 | 2 | 3 | 84.7 | |||||
hematocrit | 4 | 3 | 4 | 84.3 | |||||
myeloid white cell count | 2 | 1 | 2 | 78.5 | |||||
urate measurement | 4 | 4 | 4 | 75 | |||||
platelet crit | 2 | 1 | 2 | 73.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neutrophil count | 3 | 84.7 | |||||
hematocrit | 4 | 84.3 | |||||
myeloid white cell count | 2 | 78.5 | |||||
urate measurement | 4 | 75 | |||||
platelet crit | 2 | 73.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | activin A receptor like type 1 | VGNC:8313 | 451910 | |||||
Macaque | activin A receptor like type 1 | 696471 | ||||||
Mouse | MGI:1338946 | 11482 | ||||||
Rat | RGD:2029 | 25237 | ||||||
Dog | activin A receptor like type 1 | VGNC:37566 | 477603 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | activin A receptor like type 1 | |||||
Macaque | activin A receptor like type 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | activin A receptor like type 1 | |||||
PMID | Year | Title |
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