SREBF1
Sterol regulatory element-binding protein 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
disease perturbation | 1 | ||
chemical | 0.93 | ||
kinase | 0.92 | ||
biological term | 0.9 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of gene expression by SREBF (SREBP) | ||||
Reactome | Circadian Clock | ||||
Reactome | Developmental Biology | ||||
Reactome | FOXO-mediated transcription | ||||
Reactome | FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of gene expression by SREBF (SREBP) | ||||
Circadian Clock | ||||
Developmental Biology | ||||
FOXO-mediated transcription | ||||
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Direct Assay (IDA) | ParkinsonsUK-UCL | |||
Inferred from Direct Assay (IDA) | ParkinsonsUK-UCL | |||
Inferred from Direct Assay (IDA) | HGNC | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
waist-hip ratio | 2 | 7 | 7 | 89.1 | |||||
BMI-adjusted waist-hip ratio | 2 | 7 | 7 | 88.2 | |||||
lymphocyte count | 2 | 2 | 2 | 86.8 | |||||
sex hormone-binding globulin measurement | 2 | 1 | 2 | 81.9 | |||||
4 | 3 | 3 | 1.1 | 77.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
waist-hip ratio | 7 | 89.1 | |||||
BMI-adjusted waist-hip ratio | 7 | 88.2 | |||||
lymphocyte count | 2 | 86.8 | |||||
sex hormone-binding globulin measurement | 2 | 81.9 | |||||
3 | 1.1 | 77.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | sterol regulatory element binding transcription factor 1 | 706972 | ||||||
Mouse | MGI:107606 | 20787 | ||||||
Rat | RGD:69423 | 78968 | ||||||
Dog | sterol regulatory element binding transcription factor 1 | VGNC:46795 | 403475 | |||||
Horse | sterol regulatory element binding transcription factor 1 | VGNC:23576 | 100052283 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | sterol regulatory element binding transcription factor 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | sterol regulatory element binding transcription factor 1 | |||||
Horse | sterol regulatory element binding transcription factor 1 | |||||
PMID | Year | Title |
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