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Tbio
UGT2B10
UDP-glucuronosyltransferase 2B10

Protein Summary
Description
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000265403
  • ENSP00000265403
  • ENSG00000109181
  • ENST00000458688
  • ENSP00000413420
  • ENST00000615213
  • ENSP00000478760
  • ENSG00000275190
  • ENST00000627047
  • ENSP00000486876

Symbol
  • UDPGT2B10
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
pathway
0.61
gene perturbation
0.59
cell line
0.54
cellular component
0.5
disease perturbation
0.49


Related Tools
Target Illumination GWAS Analytics (TIGA)
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TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.38   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 119   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.38   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 119   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (28)
Items per page:
1 – 5 of 28
GWAS Trait
EFO ID
ENSG ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cotinine glucuronidation measurement
1
4
4
97.8
cotinine glucuronidation measurement
1
4
4
97.8
sex hormone-binding globulin measurement
6
3
6
94.2
sex hormone-binding globulin measurement
6
3
6
94.2
cotinine measurement
4
4
4
89.6
Items per page:
1 – 5 of 28
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
cotinine glucuronidation measurement
4
97.8
cotinine glucuronidation measurement
4
97.8
sex hormone-binding globulin measurement
6
94.2
sex hormone-binding globulin measurement
6
94.2
cotinine measurement
4
89.6
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-P36537-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (22)
Biological oxidations (R-HSA-211859)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Biological oxidations
Reactome
Glucuronidation
Reactome
Metabolism
Reactome
Phase II - Conjugation of compounds
Name
Explore in Pharos
Explore in Source
Biological oxidations
Glucuronidation
Metabolism
Phase II - Conjugation of compounds
Protein-Protein Interactions (95)
1 – 10 of 95
DIO1
Tclin
Family:  Enzyme
Novelty:  0.01035036
Score:  0.913
Data Source:  STRINGDB
ADH6
Tbio
Family:  Enzyme
Novelty:  0.01102438
Score:  0.912
Data Source:  STRINGDB
ADH1B
Tclin
Family:  Enzyme
Novelty:  0.00204308
Score:  0.906
Data Source:  STRINGDB
DIO2
Tbio
Family:  Enzyme
Novelty:  0.00173094
Score:  0.905
Data Source:  STRINGDB
CYP2A6
Tchem
Novelty:  0.00105285
Score:  0.875
Data Source:  STRINGDB
UGT2B11
Tbio
Family:  Enzyme
Novelty:  0.13396162
Score:  0.83
Data Source:  STRINGDB
CYP1A1
Tchem
Novelty:  0.0002404
Score:  0.791
Data Source:  STRINGDB
AOX1
Tchem
Family:  Enzyme
Novelty:  0.0025823
Score:  0.78
Data Source:  STRINGDB
SERPINA7
Tbio
Novelty:  0.00078476
Score:  0.778
Data Source:  STRINGDB
CYP2B6
Tchem
Novelty:  0.00018351
Score:  0.775
Data Source:  STRINGDB
Publication Statistics
PubMed Score  38.38

PubMed score by year
PubTator Score  27.99

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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