FLT4
Vascular endothelial growth factor receptor 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 1 | ||
molecular function | 0.99 | ||
biological process | 0.87 | ||
PubMedID | 0.77 | ||
biological term | 0.72 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | NOTCH4 Intracellular Domain Regulates Transcription | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by NOTCH | ||||
Reactome | Signaling by NOTCH4 | ||||
Reactome | Signaling by Receptor Tyrosine Kinases | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
NOTCH4 Intracellular Domain Regulates Transcription | ||||
Signal Transduction | ||||
Signaling by NOTCH | ||||
Signaling by NOTCH4 | ||||
Signaling by Receptor Tyrosine Kinases | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular volume | 1 | 1 | 1 | 63.1 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 49.5 | |||||
serum albumin measurement | 1 | 1 | 1 | 44.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular volume | 1 | 63.1 | |||||
mean reticulocyte volume | 1 | 49.5 | |||||
serum albumin measurement | 1 | 44.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | fms related tyrosine kinase 4 | VGNC:6876 | 462339 | |||||
Macaque | fms related tyrosine kinase 4 | 716412 | ||||||
Mouse | MGI:95561 | 14257 | ||||||
Rat | RGD:621737 | 114110 | ||||||
Dog | fms related tyrosine kinase 4 | VGNC:40910 | 481464 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | fms related tyrosine kinase 4 | |||||
Macaque | fms related tyrosine kinase 4 | |||||
Mouse | ||||||
Rat | ||||||
Dog | fms related tyrosine kinase 4 | |||||
PMID | Year | Title |
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