Protein Summary
Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells.
- ENST00000330927
- ENSP00000333779
- ENSG00000185862
- ENST00000577894
- ENSP00000462682
- EVDB
- EVDB
- CD361
- D17S376
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
PubMedID | 0.8 | ||
kinase perturbation | 0.71 | ||
transcription factor perturbation | 0.61 | ||
gene perturbation | 0.58 | ||
tissue | 0.52 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 9.22 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 160 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 9.22 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 160 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 6
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0