YWHAB
14-3-3 protein beta/alpha
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
hub protein | 1 | ||
interacting protein | 1 | ||
kinase perturbation | 1 | ||
biological process | 0.98 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | ARMS-mediated activation | ||||
Reactome | Activation of BAD and translocation to mitochondria | ||||
Reactome | Activation of BH3-only proteins | ||||
Reactome | Adaptive Immune System | ||||
Reactome | Apoptosis | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
ARMS-mediated activation | ||||
Activation of BAD and translocation to mitochondria | ||||
Activation of BH3-only proteins | ||||
Adaptive Immune System | ||||
Apoptosis | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | BHF-UCL | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 1 | 2 | 2 | 90.2 | |||||
basophil count | 1 | 1 | 1 | 74.3 | |||||
basophil percentage of leukocytes | 1 | 1 | 1 | 74.2 | |||||
chronotype measurement | 2 | 1 | 1 | 1 | 63.7 | ||||
blood protein measurement | 1 | 1 | 1 | 47.7 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 2 | 90.2 | |||||
basophil count | 1 | 74.3 | |||||
basophil percentage of leukocytes | 1 | 74.2 | |||||
chronotype measurement | 1 | 1 | 63.7 | ||||
blood protein measurement | 1 | 47.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta | VGNC:10069 | 458272 | |||||
Macaque | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta | 717788 | ||||||
Mouse | MGI:1891917 | 54401 | ||||||
Rat | RGD:61998 | 56011 | ||||||
Dog | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta | VGNC:48508 | 477237 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta | |||||
Macaque | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta | |||||
Mouse | ||||||
Rat | ||||||
Dog | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta | |||||
PMID | Year | Title |
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