CDC27
Cell division cycle protein 27 homolog
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
hub protein | 0.99 | ||
transcription factor perturbation | 0.96 | ||
biological process | 0.94 | ||
interacting protein | 0.94 | ||
histone modification site profile | 0.92 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | APC-Cdc20 mediated degradation of Nek2A | ||||
Reactome | APC/C-mediated degradation of cell cycle proteins | ||||
Reactome | APC/C:Cdc20 mediated degradation of Cyclin B | ||||
Reactome | APC/C:Cdc20 mediated degradation of Securin | ||||
Reactome | APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
APC-Cdc20 mediated degradation of Nek2A | ||||
APC/C-mediated degradation of cell cycle proteins | ||||
APC/C:Cdc20 mediated degradation of Cyclin B | ||||
APC/C:Cdc20 mediated degradation of Securin | ||||
APC/C:Cdc20 mediated degradation of mitotic proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
platelet count | 1 | 1 | 1 | 63.7 | |||||
serum non-albumin protein measurement | 1 | 2 | 2 | 57.7 | |||||
serum urea measurement | 1 | 1 | 1 | 55.2 | |||||
eosinophil count | 1 | 1 | 1 | 44.2 | |||||
eosinophil percentage of leukocytes | 1 | 1 | 1 | 39.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
platelet count | 1 | 63.7 | |||||
serum non-albumin protein measurement | 2 | 57.7 | |||||
serum urea measurement | 1 | 55.2 | |||||
eosinophil count | 1 | 44.2 | |||||
eosinophil percentage of leukocytes | 1 | 39.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | cell division cycle 27 | VGNC:12048 | 454815 | |||||
Macaque | cell division cycle 27 | 717321 | ||||||
Mouse | MGI:102685 | 217232 | ||||||
Rat | RGD:1304921 | 360643 | ||||||
Dog | cell division cycle 27 | VGNC:53202 | 490924 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | cell division cycle 27 | |||||
Macaque | cell division cycle 27 | |||||
Mouse | ||||||
Rat | ||||||
Dog | cell division cycle 27 | |||||
PMID | Year | Title |
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