Protein Summary
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]
- ENST00000325602
- ENSP00000320376
- ENSG00000181631
- GPR86
- GPR94
- GPCR1
- GPR86
- GPR94
- P2Y13
- SP174
- FKSG77
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
cell type or tissue | 0.7 | ||
gene perturbation | 0.65 | ||
tissue sample | 0.59 | ||
ligand (chemical) | 0.56 | ||
tissue | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.14 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 339 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.14 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 339 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 12
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drugs: 3
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (3)
Active Ligands (12)
Protein-Protein Interactions (273)
Nearest Tclin Targets
Pathways (21)
Reactome (8)
KEGG (1)
WikiPathways (12)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
Reactome | G alpha (i) signalling events | ||||
Reactome | GPCR downstream signalling | ||||
Reactome | GPCR ligand binding | ||||
Reactome | Nucleotide-like (purinergic) receptors | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Class A/1 (Rhodopsin-like receptors) | ||||
G alpha (i) signalling events | ||||
GPCR downstream signalling | ||||
GPCR ligand binding | ||||
Nucleotide-like (purinergic) receptors | ||||
Viral Interactions (0)
Gene Ontology Terms (7)
Functions (1)
Components (3)
Processes (3)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Disease Associations (null)
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
lymphocyte count | 1 | 1 | 1 | 74.6 | |||||
myeloid white cell count | 1 | 1 | 1 | 74.2 | |||||
leukocyte count | 1 | 1 | 1 | 64.4 | |||||
monocyte count | 1 | 1 | 1 | 42.3 | |||||
anti-Epstein Barr virus antibody measurement | 1 | 1 | 1 | 21.5 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
lymphocyte count | 1 | 74.6 | |||||
myeloid white cell count | 1 | 74.2 | |||||
leukocyte count | 1 | 64.4 | |||||
monocyte count | 1 | 42.3 | |||||
anti-Epstein Barr virus antibody measurement | 1 | 21.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (9)
1 – 5 of 9
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | purinergic receptor P2Y13 | VGNC:7992 | 738859 | |||||
Mouse | MGI:1921441 | 74191 | ||||||
Rat | RGD:1302941 | 310444 | ||||||
Dog | purinergic receptor P2Y13 | VGNC:44215 | 102155830 | |||||
Horse | purinergic receptor P2Y13 | VGNC:21111 | 100050217 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | purinergic receptor P2Y13 | |||||
Mouse | ||||||
Rat | ||||||
Dog | purinergic receptor P2Y13 | |||||
Horse | purinergic receptor P2Y13 | |||||
Publication Statistics
PubMed Score 62.14
PubMed score by year
PubTator Score 27.54
PubTator score by year
Patents
Patents by year
Related Publications
Text Mined References (13)
GeneRif Annotations (4)
Items per page:
0 of 0
PMID | Year | Title |
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