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Tchem
P2RY13
P2Y purinoceptor 13

Protein Summary
Description
Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is activated by ADP. [provided by RefSeq, Sep 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000325602
  • ENSP00000320376
  • ENSG00000181631

Symbol
  • GPR86
  • GPR94
  • GPCR1
  • GPR86
  • GPR94
  • P2Y13
  • SP174
  • FKSG77
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.7
gene perturbation
0.65
tissue sample
0.59
ligand (chemical)
0.56
tissue
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 62.14   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 339   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 62.14   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 339   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 12
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 3
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (273)
TMIGD3
Tchem
Novelty:  0.00089511
Score:  0.966
Data Source:  STRINGDB
ADORA3
Tchem
Family:  GPCR
Novelty:  0.00089511
Score:  0.966
Data Source:  STRINGDB
TAS2R16
Tchem
Family:  GPCR
Novelty:  0.03181719
Score:  0.96
Data Source:  STRINGDB
TAS2R38
Tchem
Family:  GPCR
Novelty:  0.004625
Score:  0.951
Data Source:  STRINGDB
ADORA1
Tclin
Family:  GPCR
Novelty:  0.00043697
Score:  0.95
Data Source:  STRINGDB
P2RY12
Tclin
Family:  GPCR
Novelty:  0.00035406
Score:  0.936
Data Source:  STRINGDB
CX3CR1
Tchem
Family:  GPCR
Novelty:  0.00114874
Score:  0.933
Data Source:  STRINGDB
P2RY14
Tchem
Family:  GPCR
Novelty:  0.0135462
Score:  0.931
Data Source:  STRINGDB
CXCR1
Tchem
Family:  GPCR
Novelty:  0.00224501
Score:  0.931
Data Source:  STRINGDB
FPR1
Tchem
Family:  GPCR
Novelty:  0.00256884
Score:  0.93
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (21)
Class A/1 (Rhodopsin-like receptors) (R-HSA-373076)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Class A/1 (Rhodopsin-like receptors)
Reactome
G alpha (i) signalling events
Reactome
GPCR downstream signalling
Reactome
GPCR ligand binding
Reactome
Nucleotide-like (purinergic) receptors
Name
Explore in Pharos
Explore in Source
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
GPCR downstream signalling
GPCR ligand binding
Nucleotide-like (purinergic) receptors
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
1
1
74.6
myeloid white cell count
1
1
1
74.2
leukocyte count
1
1
1
64.4
monocyte count
1
1
1
42.3
anti-Epstein Barr virus antibody measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
1
74.6
myeloid white cell count
1
74.2
leukocyte count
1
64.4
monocyte count
1
42.3
anti-Epstein Barr virus antibody measurement
1
21.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
purinergic receptor P2Y13
VGNC:7992
738859
Mouse
MGI:1921441
74191
Rat
RGD:1302941
310444
Dog
purinergic receptor P2Y13
VGNC:44215
102155830
Horse
purinergic receptor P2Y13
VGNC:21111
100050217
Species
Name
OMA
EggNOG
Inparanoid
Chimp
purinergic receptor P2Y13
Mouse
Rat
Dog
purinergic receptor P2Y13
Horse
purinergic receptor P2Y13
Publication Statistics
PubMed Score 62.14
PubMed score by year
PubTator Score 27.54
PubTator score by year
Patents
Patents by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title