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Tchem
P2RY10
Putative P2Y purinoceptor 10

Protein Summary
Description
Putative receptor for purines coupled to G-proteins. The protein encoded by this gene belongs to the family of G-protein coupled receptors that are preferentially activated by adenosine and uridine nucleotides. There is a pseudogene for this gene nearby on chromosome X. Multiple alternatively spliced transcripts have been observed. [provided by RefSeq, Apr 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000171757
  • ENSP00000171757
  • ENSG00000078589
  • ENST00000544091
  • ENSP00000443138

Symbol
  • P2Y10
  • LYPSR2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
co-expressed gene
1
cell type or tissue
0.78
gene perturbation
0.68
tissue sample
0.55
tissue
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.16   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 150   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.16   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 150   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 28
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Protein-Protein Interactions (193)
LPAR3
Tchem
Family:  GPCR
Novelty:  0.00590837
Score:  0.961
Data Source:  STRINGDB
LPAR2
Tchem
Family:  GPCR
Novelty:  0.00794134
Score:  0.96
Data Source:  STRINGDB
LPAR1
Tchem
Family:  GPCR
Novelty:  0.00318056
Score:  0.96
Data Source:  STRINGDB
LPAR5
Tchem
Family:  GPCR
Novelty:  0.01883439
Score:  0.958
Data Source:  STRINGDB
GPR132
Tchem
Family:  GPCR
Novelty:  0.00453902
Score:  0.928
Data Source:  STRINGDB
GPR65
Tbio
Family:  GPCR
Novelty:  0.02341854
Score:  0.928
Data Source:  STRINGDB
XCL2
Tbio
Novelty:  0.05252386
Score:  0.924
Data Source:  STRINGDB
TBXA2R
Tclin
Family:  GPCR
Novelty:  0.00571066
Score:  0.923
Data Source:  STRINGDB
XCL1
Tbio
Novelty:  0.00429108
Score:  0.92
Data Source:  STRINGDB
P2RY11
Tchem
Family:  GPCR
Novelty:  0.01380362
Score:  0.916
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (10)
Class A/1 (Rhodopsin-like receptors) (R-HSA-373076)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 8
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Class A/1 (Rhodopsin-like receptors)
Reactome
G alpha (q) signalling events
Reactome
GPCR downstream signalling
Reactome
GPCR ligand binding
Reactome
Nucleotide-like (purinergic) receptors
Name
Explore in Pharos
Explore in Source
Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
GPCR downstream signalling
GPCR ligand binding
Nucleotide-like (purinergic) receptors
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
Genetic Construct
P2RY10-Tango
image for P2RY10-Tango
Details:
  • Vector:  addgene66469
  • Vector backbone:  pcDNA3.1(+)
  • Promoter:  CMV
  • Tag:  FLAG
Data:
  • P2RY10-Tango
Order Genetic Construct from:
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1926076
78826
Rat
RGD:1561912
317219
Dog
P2Y receptor family member 10
VGNC:49748
491980
Horse
putative P2Y purinoceptor 10
100072611
Cow
P2Y receptor family member 10
VGNC:32524
515172
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
P2Y receptor family member 10
Horse
putative P2Y purinoceptor 10
Cow
P2Y receptor family member 10
Publication Statistics
PubMed Score 7.16
PubMed score by year
PubTator Score 6.30
PubTator score by year
Patents
Patents by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title