Protein Summary
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. [provided by RefSeq, Jul 2008]
- ENST00000211402
- ENSP00000211402
- ENSG00000096171
- ENST00000375663
- ENSP00000364815
- ENSG00000204394
- ENST00000422694
- ENSP00000401121
- ENSG00000224264
- ENST00000435657
- ENSP00000415316
- ENSG00000231116
- ENST00000457796
- ENSP00000403359
- ENSG00000226589
- G7A
- VARS2
- G7A
- VARS1
- VARS2
- NDMSCA
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 1 | ||
molecular function | 0.95 | ||
interacting protein | 0.94 | ||
transcription factor perturbation | 0.84 | ||
protein complex | 0.81 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 184.58 (req: < 5)
Gene RIFs: 7 (req: <= 3)
Antibodies: 171 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 184.58 (req: >= 5)
Gene RIFs: 7 (req: > 3)
Antibodies: 171 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 3
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0