Tbio ELAVL4 ELAV-like protein 4

Protein Summary

Description

May play a role in neuron-specific RNA processing. Protects CDKN1A mRNA from decay by binding to its 3'-UTR (By similarity). Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF and FOS mRNA.

Uniprot Accession IDs

• P26378
• B1APY6
• B1APY7
• B7Z4G7
• Q8IYD4
• Q96J74
• Q96J75
• Q9UD24

Gene Name

• ELAVL4

Ensembl ID

• ENST00000371823
• ENSP00000360888
• ENSG00000162374
• ENST00000371824
• ENSP00000360889
• ENST00000371827
• ENSP00000360892
• ENST00000448907
• ENSP00000399939

Symbol

• HUD
• PNEM
• HUD
• PNEM

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor	0.82
cellular component	0.66
virus perturbation	0.64
PubMedID	0.61
protein domain	0.58

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 437.44   (req: < 5)

Gene RIFs: 37   (req: <= 3)

Antibodies: 217   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 437.44   (req: >= 5)

Gene RIFs: 37   (req: > 3)

Antibodies: 217   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0