PAX6
Paired box protein Pax-6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 1 | ||
molecular function | 1 | ||
co-expressed gene | 0.97 | ||
kinase perturbation | 0.96 | ||
PubMedID | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Activation of HOX genes during differentiation | ||||
Reactome | Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Reactome | Developmental Biology | ||||
Reactome | Incretin synthesis, secretion, and inactivation | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Activation of HOX genes during differentiation | ||||
Activation of anterior HOX genes in hindbrain development during early embryogenesis | ||||
Developmental Biology | ||||
Incretin synthesis, secretion, and inactivation | ||||
Metabolism of proteins | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Traceable Author Statement (TAS) | ProtInc | |||
Traceable Author Statement (TAS) | ProtInc | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
neuroticism measurement | 5 | 5 | 4 | 6.2 | 77 | ||||
wellbeing measurement | 3 | 2 | 3 | 72.1 | |||||
depressive symptom measurement | 3 | 2 | 3 | 69.6 | |||||
worry measurement | 2 | 2 | 1 | 5.9 | 60.1 | ||||
3 | 1 | 1 | 1 | 35 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
neuroticism measurement | 4 | 6.2 | 77 | ||||
wellbeing measurement | 3 | 72.1 | |||||
depressive symptom measurement | 3 | 69.6 | |||||
worry measurement | 1 | 5.9 | 60.1 | ||||
1 | 1 | 35 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | paired box 6 | VGNC:1088 | 737387 | |||||
Macaque | paired box 6 | 695746 | ||||||
Mouse | MGI:97490 | 18508 | ||||||
Rat | RGD:3258 | 25509 | ||||||
Horse | paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | paired box 6 | |||||
Macaque | paired box 6 | |||||
Mouse | ||||||
Rat | ||||||
Horse | paired box 6 [Source:HGNC Symbol;Acc:HGNC:8620] | |||||
PMID | Year | Title |
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