Tbio AZGP1 Zinc-alpha-2-glycoprotein

Protein Summary

Description

Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids.

Uniprot Accession IDs

• P25311
• D6W5T8
• O60386
• Q5XKQ4
• Q8N4N0
• Zn-alpha-2-GP

Gene Name

• AZGP1

Ensembl ID

• ENST00000292401
• ENSP00000292401
• ENSG00000160862

Symbol

• ZAG
• ZNGP1
• ZAG
• ZA2G

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
protein domain	0.97
interacting protein	0.76
molecular function	0.73
kinase perturbation	0.71
disease perturbation	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 319.98   (req: < 5)

Gene RIFs: 100   (req: <= 3)

Antibodies: 312   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 319.98   (req: >= 5)

Gene RIFs: 100   (req: > 3)

Antibodies: 312   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0