Protein Summary
Catalyzes the conversion of dTMP to dTDP.
- ENST00000305784
- ENSP00000304802
- ENSG00000168393
- CDC8
- TMPK
- TYMK
- CDC8
- TMPK
- TYMK
- PP3731
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
kinase perturbation | 1 | ||
virus perturbation | 0.99 | ||
interacting protein | 0.98 | ||
transcription factor perturbation | 0.97 | ||
molecular function | 0.94 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 124.38 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 403 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 124.38 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 403 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 14
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (159)
PCMT1
Family: Enzyme
Novelty: 0.01414946
p_int: 0.999779746
p_ni: 0.000220254
Score: 0.332
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets (4)
Upstream (1)
Downstream (3)
1 – 1 of 1
Pathways (10)
Reactome (3)
KEGG (2)
PathwayCommons (3)
UniProt (1)
WikiPathways (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Interconversion of nucleotide di- and triphosphates | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of nucleotides | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Interconversion of nucleotide di- and triphosphates | ||||
Metabolism | ||||
Metabolism of nucleotides | ||||
Viral Interactions (0)
Gene Ontology Terms (20)
Functions (5)
Components (6)
Processes (9)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (24)
Items per page:
1 – 5 of 24
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
6 | 2 | 2 | 1.1 | 90.7 | |||||
eosinophil count | 3 | 1 | 3 | 86.9 | |||||
blood protein measurement | 1 | 1 | 1 | 86.5 | |||||
10 | 1 | 0 | 1.1 | 86.2 | |||||
eosinophil percentage of leukocytes | 2 | 1 | 2 | 86.1 | |||||
Items per page:
1 – 5 of 24
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
2 | 1.1 | 90.7 | |||||
eosinophil count | 3 | 86.9 | |||||
blood protein measurement | 1 | 86.5 | |||||
0 | 1.1 | 86.2 | |||||
eosinophil percentage of leukocytes | 2 | 86.1 | |||||
Find similar targets by:
IDG Resources
Orthologs (13)
1 – 5 of 13
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | deoxythymidylate kinase | VGNC:368 | 744320 | |||||
Macaque | deoxythymidylate kinase | 701781 | ||||||
Mouse | MGI:108396 | 21915 | ||||||
Rat | RGD:1309614 | 301622 | ||||||
Horse | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | |||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | deoxythymidylate kinase | |||||
Macaque | deoxythymidylate kinase | |||||
Mouse | ||||||
Rat | ||||||
Horse | deoxythymidylate kinase [Source:HGNC Symbol;Acc:HGNC:3061] | |||||
Publication Statistics
PubMed Score 124.38
PubMed score by year
PubTator Score 84.68
PubTator score by year
Patents
Patents by year
Related Publications
Text Mined References (16)
GeneRif Annotations (1)
Items per page:
0 of 0
PMID | Year | Title |
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