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Tclin
CA6
Carbonic anhydrase 6

Protein Summary
Description
Reversible hydration of carbon dioxide. Its role in saliva is unknown. The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000377436
  • ENSP00000366654
  • ENSG00000131686
  • ENST00000377442
  • ENSP00000366661
  • ENST00000377443
  • ENSP00000366662

Symbol
  • CA-VI
  • GUSTIN
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.91
protein domain
0.58
hub protein
0.53
cell line
0.5
cellular component
0.47


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 420.14   (req: < 5)
Gene RIFs: 20   (req: <= 3)
Antibodies: 331   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 420.14   (req: >= 5)
Gene RIFs: 20   (req: > 3)
Antibodies: 331   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 222
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 15