FBL
rRNA 2'-O-methyltransferase fibrillarin
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
disease perturbation | 1 | ||
interacting protein | 1 | ||
kinase perturbation | 1 | ||
co-expressed gene | 0.89 | ||
transcription factor binding site profile | 0.87 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Major pathway of rRNA processing in the nucleolus and cytosol | ||||
Reactome | Metabolism of RNA | ||||
Reactome | rRNA modification in the nucleus and cytosol | ||||
Reactome | rRNA processing | ||||
Reactome | rRNA processing in the nucleus and cytosol | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Major pathway of rRNA processing in the nucleolus and cytosol | ||||
Metabolism of RNA | ||||
rRNA modification in the nucleus and cytosol | ||||
rRNA processing | ||||
rRNA processing in the nucleus and cytosol | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
eosinophil count | 2 | 2 | 2 | 93.5 | ||||||
eosinophil count | 2 | 2 | 2 | 93.5 | ||||||
eosinophil percentage of leukocytes | 1 | 1 | 1 | 84.6 | ||||||
eosinophil percentage of leukocytes | 1 | 1 | 1 | 84.6 | ||||||
eosinophil percentage of granulocytes | 1 | 1 | 1 | 83.7 | ||||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
eosinophil count | 2 | 93.5 | |||||
eosinophil count | 2 | 93.5 | |||||
eosinophil percentage of leukocytes | 1 | 84.6 | |||||
eosinophil percentage of leukocytes | 1 | 84.6 | |||||
eosinophil percentage of granulocytes | 1 | 83.7 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | fibrillarin | VGNC:11012 | 456031 | |||||
Mouse | MGI:95486 | 14113 | ||||||
Rat | RGD:1305542 | 292747 | ||||||
Dog | fibrillarin | VGNC:40748 | 476460 | |||||
Horse | fibrillarin | VGNC:17928 | 100064571 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | fibrillarin | |||||
Mouse | ||||||
Rat | ||||||
Dog | fibrillarin | |||||
Horse | fibrillarin | |||||
PMID | Year | Title |
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